alleryIn humans, the ascending limb of Henle is impermeable to water mainly because
ATight junctions block all water transit
BAquaporin channels are absent in it
CAldosterone insertion of channels here
DADH closes existing water channels there
Answer & Solution
Correct answer: B. Aquaporin channels are absent in it
The thick ascending limb lacks aquaporins, so water cannot follow Na+ and Cl-.
This dissociation between solute and water transport is the key to building the medullary osmotic gradient.
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