ADH (vasopressin) acts mainly on the
APCT to reabsorb glucose actively across tubule
BCollecting duct increasing water reabsorption
CAscending limb pumping sodium out actively
DGlomerulus to alter filtration rate at apex
Answer & Solution
Correct answer: B. Collecting duct increasing water reabsorption
ADH from the posterior pituitary inserts aquaporin-2 channels into the apical membrane of collecting-duct cells, increasing water reabsorption and concentrating urine. Diabetes insipidus arises from ADH deficiency or resistance.
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