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Phenylketonuria arises from a mutation in the gene for which enzyme?

APhenylalanine hydroxylase
BTyrosine kinase enzyme
CGlucose-6-phosphatase
DDNA ligase enzyme
Answer & Solution
Correct answer: A. Phenylalanine hydroxylase
The mutated enzyme cannot convert phenylalanine to tyrosine, so a single gene causes mental retardation and reduced pigmentation.
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