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HomeNEET UG › Organic Chemistry › The $$\mathrm{pK}_{\mathrm{a}_1}$$ and $$\mathrm…

The $$\mathrm{pK}_{\mathrm{a}_1}$$ and $$\mathrm{pK}_{\mathrm{a}_2}$$ of an amino acid are 2.3 and 9.7 respectively. The iso electric point of the amino acid is

A6.0
B3.7
C12.0
D7.4
Answer & Solution
Correct answer: A. 6.0
For an amino acid with no ionizable side chain, the isoelectric point is the average of the two given values. $$pI=\frac{pK_{a_1}+pK_{a_2}}{2}$$ $$pI=\frac{2.3+9.7}{2}$$ $$pI=\frac{12.0}{2}=6.0$$ On checking the options, $6.0$ matches option $A$.
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