The first MAJOR recombinant DNA pharmaceutical, released commercially in 1982, was:
- Recombinant human growth hormone
- Hepatitis B vaccine (recombinant)
- Erythropoietin (kidney patients)
- Recombinant human insulin (Humulin)
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Correct answer: D. Recombinant human insulin (Humulin)
HUMULIN (Eli Lilly, 1982) was the first commercial rDNA drug: human insulin produced by genetically modified E. coli.
Before that, insulin came from animal pancreases.
Hepatitis B recombinant vaccine came later (1986).