The empirical rule 'like dissolves like' predicts that:
- Solubility depends only on temperature
- Polar solutes dissolve well in polar solvents
- All solids dissolve in all liquids
- Polar solutes dissolve well in non-polar solvents
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Correct answer: B. Polar solutes dissolve well in polar solvents
'Like dissolves like' — substances with similar intermolecular forces dissolve in each other.
Polar in polar (NaCl in water), non-polar in non-polar (cholesterol in benzene).
Mismatched polarities give low solubility.