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By which mechanism does alcohol act as a diuretic?
AIt inhibits the release of renin
BIt increases aldosterone release
CIt blocks the sodium potassium pump
DIt inhibits the release of ADH
Answer & Solution
Correct answer: D. It inhibits the release of ADH
1. A diuretic increases urine output and so decreases water conservation.
2. Antidiuretic hormone normally drives water recovery from the collecting tubules.
3. Alcohol inhibits the release of that hormone, so less water is recovered and urine volume rises.
4. Caffeine taken in high concentrations also acts as a diuretic.
5. Increasing aldosterone would conserve sodium and water, the opposite of a diuretic effect.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 26 "Fluid, Electrolyte, and Acid-Base Balance", section Role of ADH_
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