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Under the influence of aldosterone, what happens to sodium and potassium in the distal tubule?
ABoth sodium and potassium are excreted
BSodium is reabsorbed and potassium excreted
CPotassium is reabsorbed and sodium excreted
DBoth sodium and potassium are reabsorbed
Answer & Solution
Correct answer: B. Sodium is reabsorbed and potassium excreted
1. Aldosterone comes from the adrenal cortex and acts on the distal tubules and collecting ducts.
2. There it stimulates the synthesis and activation of the sodium and potassium pump.
3. Sodium passes from the filtrate through the tubule cells into the extracellular fluid and capillaries.
4. Water follows that sodium by osmosis, so blood sodium and blood volume both rise.
5. The effect on potassium is the reverse, and excess potassium is pumped into the filtrate.
6. So sodium is reabsorbed while potassium is excreted.
7. Reabsorbing both would leave no route for potassium disposal, which is the trap in the last option.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 26 "Fluid, Electrolyte, and Acid-Base Balance", section Aldosterone_
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