Practice free →
HomeNCK Licensing Exam (Nursing)Anatomy & PhysiologyThe Lymphatic and Immune System › A cytotoxic T cell carries the CD8 marker. Which…

A cytotoxic T cell carries the CD8 marker. Which MHC class does that marker bind?

AMHC class I
BMHC class II
CMHC class III
DMHC class IV
Answer & Solution
Correct answer: A. MHC class I
1. T cells leaving the thymus are single positives, expressing either CD4 or CD8 but never both. 2. CD4 and CD8 are adhesion molecules that hold the T cell against the antigen-presenting cell by binding the MHC molecule itself. 3. CD4-bearing T cells bind class II MHC and are associated with helper functions. 4. CD8-bearing T cells bind class I MHC and are associated with cytotoxicity, so a cytotoxic T cell reads class I. 5. Class II is the trap here, since it belongs to the helper and regulatory side, and only class I and class II take part in antigen presentation. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 21 "The Lymphatic and Immune System", section 21.3 The Adaptive Immune Response: T lymphocytes and Their Functional Types_
Solve this in the app — NCK Licensing Exam (Nursing) practice & 24k+ MCQs →
Related questions