Counting gross output, how many adenosine triphosphate and NADH molecules does glycolysis produce from one glucose molecule?
ATwo ATP and four NADH
BFour ATP and two NADH
CTwo ATP and two NADH
DFour ATP and four NADH
Answer & Solution
Correct answer: B. Four ATP and two NADH
1. Glycolysis starts with glucose and ends with two pyruvate molecules.
2. Its gross output is a total of four adenosine triphosphate molecules and two molecules of NADH.
3. Steps seven and ten each make one adenosine triphosphate, and each runs twice because the sugar was split in two.
4. Step six loads electrons onto the carrier once per three-carbon sugar, giving two NADH.
5. Answers with two adenosine triphosphate are quoting the net figure, which comes after subtracting the investment.
6. Four NADH would require the electron-loading step to run four times, which it does not.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 7 "Cellular Respiration", section 7.2 Glycolysis_
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