In a Hardy-Weinberg population the recessive phenotype (genotype aa) occurs in 16 percent of individuals. Assuming equilibrium, the frequency of heterozygous carriers (Aa) is closest to:
A{'text': '0.48, computed as 2pq with p = 0.6 and q = 0.4', 'label': 'A'}
B{'text': '0.16, the same as the homozygous recessive frequency', 'label': 'B'}
C{'text': '0.32, half the heterozygote-plus-recessive total', 'label': 'C'}
D{'text': '0.64, dominated by the homozygous dominant share', 'label': 'D'}
Answer & Solution
Correct answer: A. {'text': '0.48, computed as 2pq with p = 0.6 and q = 0.4', 'label': 'A'}
If q squared equals 0.16, then q equals 0.4 and p equals 0.6. Heterozygote frequency is 2pq, which is 2 times 0.6 times 0.4, equal to 0.48. The dominant homozygote frequency p squared is 0.36, and the total 0.36 plus 0.48 plus 0.16 equals 1.
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