In a population satisfying the Hardy-Weinberg principle for a single gene with two alleles of frequencies p and q, the frequency of heterozygotes is:
A{'text': 'p squared (the homozygous dominant frequency)', 'label': 'A'}
B{'text': 'q squared (the homozygous recessive frequency)', 'label': 'B'}
C{'text': 'p plus q (which must equal one by definition)', 'label': 'C'}
D{'text': '2pq (twice the product of the two frequencies)', 'label': 'D'}
Answer & Solution
Correct answer: D. {'text': '2pq (twice the product of the two frequencies)', 'label': 'D'}
Under Hardy-Weinberg equilibrium, genotype frequencies follow the binomial expansion of (p+q) squared, giving p squared plus 2pq plus q squared equal to 1. The heterozygote (Aa) frequency is therefore 2pq.
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