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The aldol condensation requires which structural feature on the carbonyl compound?
AA halogen on the carbonyl carbon
BNo hydrogens anywhere on the molecule
CAt least one $\alpha$-hydrogen
DAn aromatic ring directly attached to the C=O
Answer & Solution
Correct answer: C. At least one $\alpha$-hydrogen
Aldol condensation begins with a base deprotonating an **$\alpha$-hydrogen** (the H on the carbon adjacent to the carbonyl), forming an enolate ion. That enolate then attacks another carbonyl carbon nucleophilically. No $\alpha$-H, no enolate, no aldol.
**Classic counter-example.** Benzaldehyde ($\mathrm{C_6H_5CHO}$) and formaldehyde ($\mathrm{HCHO}$) *lack* $\alpha$-hydrogens, so they undergo **Cannizzaro disproportionation** with concentrated NaOH instead of aldol condensation.
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