Sister chromatids are held together at the centromere by which proteins?

1. Replication in the S phase makes two identical copies of each chromosome. 2. Those copies must stay joined until the right moment in division. 3. During DNA duplication in the S phase, each chromosome is replicated to produce two identical copies, called sister chromatids, that are held together at the centromere by cohesin proteins. 4. Histones package DNA into nucleosomes and have no role in holding sisters together. 5. Connexins build gap junctions between whole cells. _Source: OpenStax Biology for AP(R) Courses (CC BY 4.0), Ch 11 'Meiosis and Sexual Reproduction', sections 11.1-11.2_