During anaphase the sister chromatids separate because which proteins degrade?

1. Sister chromatids are held together at the centromere until the cell is ready to split them. 2. The glue holding them must be destroyed for separation to happen. 3. During anaphase the cohesin proteins degrade, and the sister chromatids separate at the centromere. 4. Histones package DNA and actin builds the contractile ring, so neither is the trigger. _Source: OpenStax Biology for AP(R) Courses (CC BY 4.0), Ch 10 'Cell Reproduction', sections 10.1-10.5_