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Compared with enveloped viruses, non-enveloped viruses stand up better to which group of conditions?
ATemperature change, pH and disinfectants
BAntiviral drugs, antibodies and interferon
CReverse transcriptase and host proteases
DUltraviolet light and gamma radiation
Answer & Solution
Correct answer: A. Temperature change, pH and disinfectants
1. An enveloped virion is wrapped in a phospholipid membrane taken from the host cell.
2. That envelope is fragile, so anything which disturbs a lipid membrane disables the virion.
3. Non-enveloped virions have only a protein capsid outside their genome and so hold up better.
4. The conditions named for that greater resistance are changes in temperature, changes in pH, and some disinfectants.
5. Resistance to antiviral drugs comes from mutation rather than from the missing envelope, so that option sets a trap.
6. Radiation and immune molecules are not the comparison being drawn, so both remaining options fail.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 21 "Viruses", section 21.1 Viral Evolution, Morphology, and Classification_
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