How often is the surface epithelium of the stomach completely replaced?
AEvery 3 to 6 days
BEvery 3 to 4 hours
CEvery 2 to 4 weeks
DEvery 6 to 8 months
Answer & Solution
Correct answer: A. Every 3 to 6 days
1. The mucosal barrier that stops the stomach digesting itself has three components.
2. A thick bicarbonate-rich mucus coat neutralizes acid, and tight junctions block juice from seeping deeper.
3. The third component is rapid replacement of damaged cells by stem cells where the glands meet the pits.
4. Because of that turnover, the surface epithelium is completely replaced every 3 to 6 days.
5. Three to four hours is the length of the gastric phase of secretion, not a turnover time.
6. Two to four weeks and six to eight months are far too slow for a surface under constant acid attack.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 23 "The Digestive System", section 23.4 The Stomach_
Keep practising The Digestive System
Browse all The Digestive System questions for HPCSA Board Exam, or explore more Anatomy & Physiology topics.
Related questions
Pick the bigger gut numberSend each enzyme to its makerCatch the brush border enzymesFill the digestive cell boardTrace food from mouth to anusAbout how much of the water reaching the small intestine is absorbed there?Vitamin B12 binds intrinsic factor. Where is the resulting complex taken up, and by what mGlucose and galactose enter intestinal cells by co-transport with sodium. How does fructos