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HomeSMLE (Saudi Medical Licensing)Anatomy & PhysiologyThe Digestive System › Cholecystokinin is produced by the duodenum. Whi…

Cholecystokinin is produced by the duodenum. Which pair of effects does it have?

ABicarbonate release and slower emptying
BPancreatic enzymes and bile release
CGastric acid release and more motility
DSlower emptying and less gastric acid
Answer & Solution
Correct answer: B. Pancreatic enzymes and bile release
1. Three hormones come out of the duodenum: secretin, cholecystokinin and gastric inhibitory peptide. 2. Cholecystokinin stimulates the secretion of pancreatic enzymes and of bile from the liver. 3. It also causes the gallbladder to release the bile it has stored. 4. So its pair of effects is pancreatic enzyme secretion together with bile release. 5. A watery bicarbonate secretion is the response to secretin, so the first option mixes the two hormones. 6. Slowing gastric emptying and inhibiting gastric secretion belong to gastric inhibitory peptide. 7. Stimulating gastric acid is the work of gastrin, which comes from the stomach rather than the duodenum. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 23 "The Digestive System", section 23.2 Digestive System Processes and Regulation_
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