Home › NEET UG › Biology › Principles Of Inheritance › Thalassemia differs from sickle-cell anaemia in …
Thalassemia differs from sickle-cell anaemia in that:
AThalassemia is a *quantitative* defect (too few globin molecules synthesised); sickle-cell is a *qualitative* defect (an abnormally functioning globin)
BThalassemia is X-linked, sickle-cell is autosomal
CThalassemia is dominant, sickle-cell is recessive
DThalassemia is curable, sickle-cell is not
Answer & Solution
Correct answer: A. Thalassemia is a *quantitative* defect (too few globin molecules synthesised); sickle-cell is a *qualitative* defect (an abnormally functioning globin)
Both are autosomal recessive blood disorders, but: **Thalassemia = quantitative** (reduced rate of α- or β-globin synthesis); **sickle-cell = qualitative** (incorrect Glu→Val substitution producing dysfunctional Hb).
Related questions
How many chromosomes are there in a normal human cell?The gain or loss of a single chromosome is called:Turner's syndrome in human females results from the loss of:Down's syndrome results from an extra copy of chromosome:In sickle-cell anaemia the red cell changes from a biconcave disc to a:A heterozygous female for haemophilia is called a:Morgan carried out his crosses using:Who proposed the chromosomal theory of inheritance?